Premature rupture of membranes at <25 weeks: a management dilemma
Article Abstract:
A significant number of newborns may survive after premature rupture of fetal membranes at 25 weeks or less of gestation. Fetuses less than 25 weeks old are not considered viable. A study examined the pregnancy outcome in 97 mothers admitted to the hospital for premature rupture of membranes at 25 weeks of gestation or less. Twenty-four mothers were diagnosed with amnionitis, or inflammation of the amniotic membrane surrounding the fetus. Nineteen infants were stillborn, 39 infants died after birth and 39 infants (40%) survived. Five percent of the infants were suffering from incomplete development of their lungs and none were suffering from any orthopedic deformities. Infants who survived had a higher birth weight and a more advanced gestational age than those who did not survive. Sixty-three percent of the infants who survived were developmentally normal at the time of their first birthday.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1993
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Transabdominal intra-amniotic endoscopic assessment of previable premature rupture of membranes
Article Abstract:
An endoscopic probe inserted into the uterus through the abdominal wall shows that spontaneous premature rupture of the fetal membranes often occurs close to the opening between the uterus and cervix. This was the conclusion of a study that used this technique on four women with premature rupture of membranes, three of which were spontaneous and one which was presumably caused by amniocentesis. In the three spontaneous cases, the rupture was always close to the cervical opening, but this was not true in the woman who received amniocentesis. The rupture was closed for up to three days by a technique called aminopatch.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1998
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Treatment of iatrogenic previable premature rupture of membranes with intra-amniotic injection of platelets and cryoprecipitate (amniopatch): preliminary experience
Article Abstract:
Injecting platelets and cryoprecipitate into the amniotic sac can seal fetal membranes that rupture prematurely. The exact location of the rupture is not important and the technique is relatively simple.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 1999
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